AstraZeneca will publish up-to-date results from its latest Covid-19 vaccine trial within 48 hours after US health officials said the drugmaker's analysis of the shot's efficacy may not have been based on all the available data.

The rare public rebuke marks the latest setback for the vaccine. which was hailed as a milestone in the fight against the Covid-19 pandemic, but has since been dogged by questions over its effectiveness and possible side effects.

AstraZeneca said results it published on Monday giving the shot an efficacy rate of 79 percent were based on an interim analysis of data through Feb 17 and it would now "immediately engage" with the panel monitoring the trial to share its full analysis...